Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13157.184 | 0.3142 | -0.4884 | 0.8492 | |||
| CAMA-1 | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13157.184 | 0.0096 | -0.9916 | 0.8492 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 0.138 | uM | 13099.184 | 1.0264 | 1.0513 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 0.691 | uM | 13099.184 | 1.1025 | 1.1992 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 3.46 | uM | 13099.184 | 1.0507 | 1.0986 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 17.3 | uM | 13099.184 | 0.8547 | 0.7166 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 86.4 | uM | 13099.184 | 0.7803 | 0.5711 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 432 | uM | 13099.184 | 0.6766 | 0.3676 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 2160 | uM | 13099.184 | 0.1193 | -0.7471 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 10800 | uM | 13099.184 | 0.0109 | -0.9753 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 54000 | uM | 13099.184 | 0.0004 | -0.9991 | 1.0279 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 0.138 | uM | 13161.184 | 0.9851 | 0.9684 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 0.691 | uM | 13161.184 | 0.9520 | 0.8983 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 3.46 | uM | 13161.184 | 0.9996 | 0.9991 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 17.3 | uM | 13161.184 | 0.9855 | 0.9693 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 86.4 | uM | 13161.184 | 0.9858 | 0.9700 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 432 | uM | 13161.184 | 0.9278 | 0.8471 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 2160 | uM | 13161.184 | 0.3397 | -0.3636 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 10800 | uM | 13161.184 | 0.2939 | -0.4541 | 0.9430 | |||
| HCC1143 | TNBC | Basal A | Methylglyoxal | 54000 | uM | 13161.184 | 0.0076 | -0.9887 | 0.9430 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 0.138 | uM | 13726.184 | 0.8154 | 0.1302 | 0.3574 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 0.691 | uM | 13726.184 | 0.9006 | 0.4922 | 0.3574 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 3.46 | uM | 13726.184 | 0.8908 | 0.4470 | 0.3574 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 17.3 | uM | 13726.184 | 0.8907 | 0.4468 | 0.3574 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 86.4 | uM | 13726.184 | 0.6818 | -0.3150 | 0.3574 |