Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12003.145 | 0.9629 | 0.9228 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12003.145 | 0.9932 | 0.9858 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12003.145 | 0.9932 | 0.9858 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12003.145 | 0.9589 | 0.9145 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12003.145 | 0.9589 | 0.9145 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12003.145 | 1.0480 | 1.1000 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12003.145 | 1.0480 | 1.1000 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12003.145 | 0.7662 | 0.5161 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12003.145 | 0.7662 | 0.5161 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12003.145 | 0.3014 | -0.4257 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12003.145 | 0.3014 | -0.4257 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12003.145 | 0.1944 | -0.6361 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12003.145 | 0.1944 | -0.6361 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12003.145 | 0.2021 | -0.6211 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12003.145 | 0.2021 | -0.6211 | 0.9611 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14296.189 | 0.9648 | 0.8948 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14296.189 | 0.9648 | 0.8948 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14296.189 | 0.9601 | 0.8809 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14296.189 | 0.9601 | 0.8809 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14296.189 | 0.9628 | 0.8891 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14296.189 | 0.9628 | 0.8891 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14296.189 | 0.9910 | 0.9730 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14296.189 | 0.9910 | 0.9730 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14296.189 | 1.0006 | 1.0019 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14296.189 | 1.0006 | 1.0019 | 0.6639 |