Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14296.189 | 0.9034 | 0.7163 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14296.189 | 0.9034 | 0.7163 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14296.189 | 0.3765 | -0.5407 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14296.189 | 0.3765 | -0.5407 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14296.189 | 0.1033 | -0.9346 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14296.189 | 0.1033 | -0.9346 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14296.189 | 1.0190 | 1.0576 | 0.6639 | |
| ZR-75-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14296.189 | 1.0190 | 1.0576 | 0.6639 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11939.145 | 0.9576 | 0.9492 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11939.145 | 0.9576 | 0.9492 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11939.145 | 0.9745 | 0.9695 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11939.145 | 0.9745 | 0.9695 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11939.145 | 0.9270 | 0.9119 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11939.145 | 0.9270 | 0.9119 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11939.145 | 0.9461 | 0.9353 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11939.145 | 0.9461 | 0.9353 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11939.145 | 0.8998 | 0.8784 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11939.145 | 0.8998 | 0.8784 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11939.145 | 0.5626 | 0.4210 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11939.145 | 0.5626 | 0.4210 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11939.145 | 0.1231 | -0.4239 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11939.145 | 0.1231 | -0.4239 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11939.145 | 0.0379 | -0.7139 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11939.145 | 0.0379 | -0.7139 | 1.6830 | |
| ZR75B | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11939.145 | 0.0233 | -0.7857 | 1.6830 |