Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10695.145 | 1.1279 | 1.2235 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10695.145 | 1.0353 | 1.0620 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10695.145 | 1.0353 | 1.0620 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10695.145 | 0.3191 | -0.2682 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10695.145 | 0.3191 | -0.2682 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10695.145 | 0.1091 | -0.7156 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10695.145 | 0.1091 | -0.7156 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10695.145 | 0.0482 | -0.8614 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10695.145 | 0.0482 | -0.8614 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10695.145 | 0.0483 | -0.8612 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10695.145 | 0.0483 | -0.8612 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10695.145 | 0.0721 | -0.8024 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10695.145 | 0.0721 | -0.8024 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11852.145 | 0.9358 | 0.9165 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11852.145 | 0.9358 | 0.9165 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11852.145 | 1.0513 | 1.0654 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11852.145 | 1.0513 | 1.0654 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11852.145 | 0.9760 | 0.9690 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11852.145 | 0.9760 | 0.9690 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11852.145 | 1.0494 | 1.0630 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11852.145 | 1.0494 | 1.0630 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11852.145 | 0.2058 | -0.2763 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11852.145 | 0.2058 | -0.2763 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11852.145 | 0.0789 | -0.6095 | 1.5550 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11852.145 | 0.0789 | -0.6095 | 1.5550 |