Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11058.145 | 0.0339 | -0.5691 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11058.145 | 0.0339 | -0.5691 | 2.2039 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14224.189 | 0.9634 | 0.9608 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14224.189 | 0.9634 | 0.9608 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14224.189 | 0.9226 | 0.9163 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14224.189 | 0.9226 | 0.9163 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14224.189 | 0.9355 | 0.9305 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14224.189 | 0.9355 | 0.9305 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14224.189 | 0.9720 | 0.9701 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14224.189 | 0.9720 | 0.9701 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14224.189 | 0.8897 | 0.8797 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14224.189 | 0.8897 | 0.8797 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14224.189 | 0.2294 | -0.0843 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14224.189 | 0.2294 | -0.0843 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14224.189 | 0.0258 | -0.7126 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14224.189 | 0.0258 | -0.7126 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14224.189 | 0.0981 | -0.4163 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14224.189 | 0.0981 | -0.4163 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14224.189 | 0.9634 | 0.9608 | 1.8849 | |
| SUM229PE | TNBC | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14224.189 | 0.9634 | 0.9608 | 1.8849 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10695.145 | 1.0655 | 1.1149 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10695.145 | 1.0655 | 1.1149 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10695.145 | 1.0207 | 1.0365 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10695.145 | 1.0207 | 1.0365 | 1.1360 | |
| SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10695.145 | 1.1279 | 1.2235 | 1.1360 |