Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14281.189 | 0.9707 | 0.8841 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14281.189 | 0.8695 | 0.5110 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14281.189 | 0.8695 | 0.5110 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14281.189 | 0.2385 | -0.8872 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14281.189 | 0.2385 | -0.8872 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14281.189 | 0.0135 | -0.9996 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14281.189 | 0.0135 | -0.9996 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14281.189 | 0.0088 | -0.9999 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14281.189 | 0.0088 | -0.9999 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14281.189 | 0.9948 | 0.9794 | 0.4986 | |
| SUM1315MO2 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14281.189 | 0.9948 | 0.9794 | 0.4986 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10819.145 | 0.9808 | 0.9824 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10819.145 | 0.9808 | 0.9824 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10819.145 | 0.9594 | 0.9626 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10819.145 | 0.9594 | 0.9626 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10819.145 | 0.9832 | 0.9847 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10819.145 | 0.9832 | 0.9847 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10819.145 | 0.9066 | 0.9127 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10819.145 | 0.9066 | 0.9127 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10819.145 | 0.8976 | 0.9041 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10819.145 | 0.8976 | 0.9041 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10819.145 | 0.0383 | -0.5472 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10819.145 | 0.0383 | -0.5472 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10819.145 | 0.0073 | -0.7863 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10819.145 | 0.0073 | -0.7863 | 2.1971 |