Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Methylglyoxal | 432 | uM | 13726.184 | 0.4939 | -0.7220 | 0.3574 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 2160 | uM | 13726.184 | 0.0083 | -1.0000 | 0.3574 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 10800 | uM | 13726.184 | 0.0115 | -1.0000 | 0.3574 | |||
| HCC1187 | TNBC | Basal A | Methylglyoxal | 54000 | uM | 13726.184 | 0.0002 | -1.0000 | 0.3574 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 0.138 | uM | 13165.184 | 0.9869 | 0.9560 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 0.691 | uM | 13165.184 | 0.9793 | 0.9308 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 3.46 | uM | 13165.184 | 0.9934 | 0.9777 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 17.3 | uM | 13165.184 | 0.9810 | 0.9363 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 86.4 | uM | 13165.184 | 0.9818 | 0.9390 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 432 | uM | 13165.184 | 0.9467 | 0.8237 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 2160 | uM | 13165.184 | 0.7139 | 0.1341 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 10800 | uM | 13165.184 | 0.3172 | -0.7106 | 0.5940 | |||
| HCC1395 | TNBC | Basal B | Methylglyoxal | 54000 | uM | 13165.184 | 0.0071 | -0.9995 | 0.5940 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13107.184 | 1.0204 | 1.0637 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13107.184 | 1.0433 | 1.1357 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13107.184 | 0.9849 | 0.9533 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 17.3 | uM | 13107.184 | 0.9604 | 0.8787 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 86.4 | uM | 13107.184 | 0.9902 | 0.9698 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 432 | uM | 13107.184 | 0.9534 | 0.8576 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 2160 | uM | 13107.184 | 0.6476 | 0.0201 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 10800 | uM | 13107.184 | 0.0881 | -0.9537 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 54000 | uM | 13107.184 | 0.0060 | -0.9993 | 0.6454 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 0.138 | uM | 13173.184 | 0.9886 | 0.9702 | 0.7656 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 0.691 | uM | 13173.184 | 0.9822 | 0.9535 | 0.7656 | |||
| HCC1428 | HR+ | Luminal | Methylglyoxal | 3.46 | uM | 13173.184 | 0.9851 | 0.9612 | 0.7656 |