Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14113.189 | 0.9707 | 0.9598 | 1.4645 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14613.189 | 0.9990 | 0.9988 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14613.189 | 0.9990 | 0.9988 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14613.189 | 0.9540 | 0.9412 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14613.189 | 0.9540 | 0.9412 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14613.189 | 0.9636 | 0.9536 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14613.189 | 0.9636 | 0.9536 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14613.189 | 0.9525 | 0.9393 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14613.189 | 0.9525 | 0.9393 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14613.189 | 0.9344 | 0.9159 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14613.189 | 0.9344 | 0.9159 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14613.189 | 0.0862 | -0.5763 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14613.189 | 0.0862 | -0.5763 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14613.189 | 0.0144 | -0.8634 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14613.189 | 0.0144 | -0.8634 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14613.189 | 0.0213 | -0.8251 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14613.189 | 0.0213 | -0.8251 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14613.189 | 0.0464 | -0.7140 | 1.5791 | |
| AU565 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14613.189 | 0.0464 | -0.7140 | 1.5791 | |
| BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10581.145 | 0.9740 | 0.9425 | 0.9044 | |
| BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10581.145 | 0.9740 | 0.9425 | 0.9044 | |
| BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10581.145 | 0.9740 | 0.9425 | 0.9044 | |
| BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10581.145 | 0.9740 | 0.9425 | 0.9044 | |
| BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10581.145 | 1.0114 | 1.0251 | 0.9044 | |
| BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10581.145 | 1.0114 | 1.0251 | 0.9044 |