Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.0213 | uM | 13558.174 | 0.9486 | 0.8230 | 0.5699 | |||
MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.107 | uM | 13558.174 | 0.8978 | 0.6553 | 0.5699 | |||
MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.533 | uM | 13558.174 | 0.5517 | -0.2956 | 0.5699 | |||
MDA-MB-361 | HER2amp | Luminal | Mebendazole | 2.67 | uM | 13558.174 | 0.6073 | -0.1664 | 0.5699 | |||
MDA-MB-361 | HER2amp | Luminal | Mebendazole | 13.3 | uM | 13558.174 | 0.4945 | -0.4188 | 0.5699 | |||
MDA-MB-361 | HER2amp | Luminal | Mebendazole | 66.7 | uM | 13558.174 | 0.4408 | -0.5250 | 0.5699 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.000171 | uM | 12959.174 | 0.9561 | 0.8289 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.000853 | uM | 12959.174 | 0.9476 | 0.7965 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.00427 | uM | 12959.174 | 0.9482 | 0.7990 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.0213 | uM | 12959.174 | 0.9482 | 0.7990 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.107 | uM | 12959.174 | 0.9518 | 0.8126 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.533 | uM | 12959.174 | 0.8680 | 0.5086 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 2.67 | uM | 12959.174 | 0.7455 | 0.1143 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 13.3 | uM | 12959.174 | 0.6517 | -0.1476 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 66.7 | uM | 12959.174 | 0.6068 | -0.2608 | 0.5020 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.000171 | uM | 13587.174 | 0.9832 | 0.9518 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.000853 | uM | 13587.174 | 0.9585 | 0.8819 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.00427 | uM | 13587.174 | 0.9571 | 0.8778 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.0213 | uM | 13587.174 | 0.9841 | 0.9543 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.107 | uM | 13587.174 | 0.9530 | 0.8664 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 0.533 | uM | 13587.174 | 0.7269 | 0.2642 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 2.67 | uM | 13587.174 | 0.5119 | -0.2364 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 13.3 | uM | 13587.174 | 0.5984 | -0.0443 | 0.6955 | |||
MDA-MB-415 | HR+ | Luminal | Mebendazole | 66.7 | uM | 13587.174 | 0.5264 | -0.2050 | 0.6955 | |||
MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.000171 | uM | 12964.174 | 0.9610 | 0.9015 | 0.7885 |