Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 0.533 | uM | 12632.174 | 0.7123 | 0.3458 | 0.8563 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 2.67 | uM | 12632.174 | 0.5256 | -0.0562 | 0.8563 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 13.3 | uM | 12632.174 | 0.2949 | -0.5194 | 0.8563 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 66.7 | uM | 12632.174 | 0.1785 | -0.7326 | 0.8563 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 0.000171 | uM | 13754.174 | 0.9459 | 0.7568 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 0.000853 | uM | 13754.174 | 0.9457 | 0.7558 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 0.00427 | uM | 13754.174 | 0.9384 | 0.7245 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 0.0213 | uM | 13754.174 | 0.9289 | 0.6842 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 0.107 | uM | 13754.174 | 0.9462 | 0.7581 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 0.533 | uM | 13754.174 | 0.8092 | 0.2209 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 2.67 | uM | 13754.174 | 0.7807 | 0.1230 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 13.3 | uM | 13754.174 | 0.7763 | 0.1085 | 0.4290 | |||
| MDA-MB-175-VII | HR+ | Luminal | Mebendazole | 66.7 | uM | 13754.174 | 0.7037 | -0.1183 | 0.4290 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.000171 | uM | 12989.174 | 0.9855 | 0.9592 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.000853 | uM | 12989.174 | 0.9310 | 0.8079 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.00427 | uM | 12989.174 | 0.9586 | 0.8840 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.0213 | uM | 12989.174 | 0.8961 | 0.7130 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.107 | uM | 12989.174 | 0.9340 | 0.8163 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.533 | uM | 12989.174 | 0.7544 | 0.3436 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 2.67 | uM | 12989.174 | 0.4895 | -0.2705 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 13.3 | uM | 12989.174 | 0.5161 | -0.2138 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 66.7 | uM | 12989.174 | 0.5275 | -0.1892 | 0.7084 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.000171 | uM | 13558.174 | 0.9916 | 0.9705 | 0.5699 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.000853 | uM | 13558.174 | 0.9476 | 0.8197 | 0.5699 | |||
| MDA-MB-361 | HER2amp | Luminal | Mebendazole | 0.00427 | uM | 13558.174 | 0.9561 | 0.8485 | 0.5699 |