Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Mebendazole | 13.3 | uM | 12949.174 | 0.4142 | 0.2581 | 1.9016 | |||
| MCF12A | NM | Basal B | Mebendazole | 66.7 | uM | 12949.174 | 0.2965 | 0.0553 | 1.9016 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 0.000171 | uM | 12657.174 | 0.9921 | 0.9853 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 0.000853 | uM | 12657.174 | 0.9448 | 0.8974 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 0.00427 | uM | 12657.174 | 0.9828 | 0.9681 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 0.0213 | uM | 12657.174 | 0.9730 | 0.9498 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 0.107 | uM | 12657.174 | 0.9653 | 0.9356 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 0.533 | uM | 12657.174 | 0.7635 | 0.5570 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 2.67 | uM | 12657.174 | 0.7247 | 0.4834 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 13.3 | uM | 12657.174 | 0.7102 | 0.4558 | 1.0776 | |||
| MCF7 | HR+ | Luminal | Mebendazole | 66.7 | uM | 12657.174 | 0.6106 | 0.2654 | 1.0776 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 0.000171 | uM | 12662.174 | 1.0082 | 1.0101 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 0.000853 | uM | 12662.174 | 0.9551 | 0.9438 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 0.00427 | uM | 12662.174 | 0.9723 | 0.9655 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 0.0213 | uM | 12662.174 | 0.9577 | 0.9471 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 0.107 | uM | 12662.174 | 0.9453 | 0.9314 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 0.533 | uM | 12662.174 | 0.2263 | -0.2040 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 2.67 | uM | 12662.174 | 0.2992 | -0.0535 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 13.3 | uM | 12662.174 | 0.3123 | -0.0279 | 1.6130 | |||
| MDA-MB-134-VI | HR+ | Luminal | Mebendazole | 66.7 | uM | 12662.174 | 0.2681 | -0.1156 | 1.6130 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 0.000171 | uM | 12632.174 | 0.9939 | 0.9858 | 0.8563 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 0.000853 | uM | 12632.174 | 0.9831 | 0.9606 | 0.8563 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 0.00427 | uM | 12632.174 | 0.9707 | 0.9316 | 0.8563 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 0.0213 | uM | 12632.174 | 0.9581 | 0.9024 | 0.8563 | |||
| MDA-MB-157 | TNBC | Basal B | Mebendazole | 0.107 | uM | 12632.174 | 0.9933 | 0.9843 | 0.8563 |