Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21NT | HER2amp | - | Mebendazole | 0.000171 | uM | 13575.174 | 0.9723 | 0.9648 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 0.000853 | uM | 13575.174 | 0.9240 | 0.9027 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 0.00427 | uM | 13575.174 | 0.9616 | 0.9512 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 0.0213 | uM | 13575.174 | 0.9645 | 0.9549 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 0.107 | uM | 13575.174 | 0.9520 | 0.9389 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 0.533 | uM | 13575.174 | 0.8067 | 0.7464 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 2.67 | uM | 13575.174 | 0.4078 | 0.1354 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 13.3 | uM | 13575.174 | 0.5650 | 0.3948 | 1.5845 | |||
| 21NT | HER2amp | - | Mebendazole | 66.7 | uM | 13575.174 | 0.4906 | 0.2760 | 1.5845 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 0.000171 | uM | 13091.174 | 0.9556 | 0.8892 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 0.000853 | uM | 13091.174 | 0.9176 | 0.7953 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 0.00427 | uM | 13091.174 | 0.9948 | 0.9869 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 0.0213 | uM | 13091.174 | 0.9785 | 0.9461 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 0.107 | uM | 13091.174 | 0.9558 | 0.8896 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 0.533 | uM | 13091.174 | 0.9354 | 0.8391 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 2.67 | uM | 13091.174 | 0.8817 | 0.7075 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 13.3 | uM | 13091.174 | 0.7667 | 0.4330 | 0.7967 | |||
| 600MPE | HR+ | Luminal | Mebendazole | 66.7 | uM | 13091.174 | 0.7201 | 0.3243 | 0.7967 | |||
| AU565 | HER2amp | Luminal | Mebendazole | 0.000171 | uM | 13030.174 | 1.0154 | 1.0357 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Mebendazole | 0.000853 | uM | 13030.174 | 0.9515 | 0.8880 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Mebendazole | 0.00427 | uM | 13030.174 | 0.8699 | 0.7012 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Mebendazole | 0.0213 | uM | 13030.174 | 0.9271 | 0.8318 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Mebendazole | 0.107 | uM | 13030.174 | 0.9229 | 0.8222 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Mebendazole | 0.533 | uM | 13030.174 | 0.4726 | -0.1620 | 0.8615 | |||
| AU565 | HER2amp | Luminal | Mebendazole | 2.67 | uM | 13030.174 | 0.5123 | -0.0799 | 0.8615 |