Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0064 | uM | 10644.142 | 1.0579 | 1.2304 | 0.5163 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.032 | uM | 10644.142 | 0.7909 | 0.2698 | 0.5163 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.16 | uM | 10644.142 | 0.8444 | 0.4415 | 0.5163 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.8 | uM | 10644.142 | 0.2388 | -0.8752 | 0.5163 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 4 | uM | 10644.142 | 0.1189 | -0.9677 | 0.5163 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 20 | uM | 10644.142 | 0.0109 | -0.9997 | 0.5163 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 100 | uM | 10644.142 | 0.0045 | -0.9999 | 0.5163 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 10874.154 | 0.9718 | 0.9266 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 10874.154 | 0.9936 | 0.9833 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 10874.154 | 0.9535 | 0.8792 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10874.154 | 0.9084 | 0.7637 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10874.154 | 0.7444 | 0.3590 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10874.154 | 0.7277 | 0.3191 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10874.154 | 0.3701 | -0.4557 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10874.154 | 0.1658 | -0.8098 | 0.7639 | |
| MX1 | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10874.154 | 0.0071 | -0.9969 | 0.7639 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 11851.154 | 1.0040 | 1.0068 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 11851.154 | 1.0562 | 1.0952 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 11851.154 | 1.0085 | 1.0144 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 11851.154 | 0.9945 | 0.9907 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 11851.154 | 0.8069 | 0.6666 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 11851.154 | 0.8535 | 0.7481 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 11851.154 | 0.7191 | 0.5111 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 11851.154 | 0.4242 | -0.0352 | 1.1765 | |
| SK-BR-3 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 11851.154 | 0.0645 | -0.8054 | 1.1765 |