Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14236.189 | 0.9452 | 0.8722 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14236.189 | 0.9452 | 0.8722 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14236.189 | 0.9369 | 0.8529 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14236.189 | 0.9369 | 0.8529 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14236.189 | 0.9610 | 0.9088 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14236.189 | 0.9610 | 0.9088 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14236.189 | 0.9626 | 0.9127 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14236.189 | 0.9626 | 0.9127 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14236.189 | 0.9528 | 0.8898 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14236.189 | 0.9528 | 0.8898 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14236.189 | 0.2349 | -0.6337 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14236.189 | 0.2349 | -0.6337 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14236.189 | 0.0701 | -0.9112 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14236.189 | 0.0701 | -0.9112 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14236.189 | 0.0242 | -0.9745 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14236.189 | 0.0242 | -0.9745 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14236.189 | 0.9953 | 0.9890 | 0.8534 | |
| CAMA-1 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14236.189 | 0.9953 | 0.9890 | 0.8534 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12112.145 | 0.9106 | 0.9050 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12112.145 | 0.9106 | 0.9050 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12112.145 | 0.8916 | 0.8843 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12112.145 | 0.8916 | 0.8843 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12112.145 | 0.9053 | 0.8992 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12112.145 | 0.9053 | 0.8992 | 1.9247 | |
| HCC1143 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12112.145 | 0.9789 | 0.9780 | 1.9247 |