Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14128.189 | 0.9000 | 0.9256 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14128.189 | 0.9000 | 0.9256 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14155.189 | 0.9704 | 0.9666 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14155.189 | 0.9704 | 0.9666 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14155.189 | 0.9626 | 0.9576 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14155.189 | 0.9626 | 0.9576 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14155.189 | 0.9506 | 0.9439 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14155.189 | 0.9506 | 0.9439 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14155.189 | 0.9868 | 0.9852 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14155.189 | 0.9868 | 0.9852 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14155.189 | 0.9570 | 0.9513 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14155.189 | 0.9570 | 0.9513 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14155.189 | 0.3402 | 0.0917 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14155.189 | 0.3402 | 0.0917 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14155.189 | 0.0121 | -0.8324 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14155.189 | 0.0121 | -0.8324 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14155.189 | 0.0095 | -0.8537 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14155.189 | 0.0095 | -0.8537 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14155.189 | 0.9971 | 0.9967 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14155.189 | 0.9971 | 0.9967 | 1.7812 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14634.189 | 0.9490 | 0.9520 | 2.1561 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14634.189 | 0.9490 | 0.9520 | 2.1561 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14634.189 | 0.9285 | 0.9324 | 2.1561 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14634.189 | 0.9285 | 0.9324 | 2.1561 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14634.189 | 0.9621 | 0.9645 | 2.1561 |