Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12239.145 | 0.9628 | 0.9648 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12239.145 | 0.1612 | -0.1495 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12239.145 | 0.1612 | -0.1495 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12239.145 | 0.0154 | -0.7170 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12239.145 | 0.0154 | -0.7170 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12239.145 | 0.0142 | -0.7277 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12239.145 | 0.0142 | -0.7277 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12239.145 | 0.0116 | -0.7519 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12239.145 | 0.0116 | -0.7519 | 2.1348 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14128.189 | 0.9547 | 0.9669 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14128.189 | 0.9547 | 0.9669 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14128.189 | 0.8897 | 0.9177 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14128.189 | 0.8897 | 0.9177 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14128.189 | 0.9481 | 0.9620 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14128.189 | 0.9481 | 0.9620 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14128.189 | 0.9239 | 0.9439 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14128.189 | 0.9239 | 0.9439 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14128.189 | 0.9174 | 0.9389 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14128.189 | 0.9174 | 0.9389 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14128.189 | 0.6631 | 0.7252 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14128.189 | 0.6631 | 0.7252 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14128.189 | 0.0217 | -0.4959 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14128.189 | 0.0217 | -0.4959 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14128.189 | 0.0091 | -0.6315 | 2.7793 | |
| HCC1806 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14128.189 | 0.0091 | -0.6315 | 2.7793 |