Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14616.189 | 0.0025 | -0.9702 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14616.189 | 0.0025 | -0.9702 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14616.189 | 0.0016 | -0.9777 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14616.189 | 0.0016 | -0.9777 | 1.4258 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10873.145 | 1.0349 | 1.0559 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10873.145 | 1.0349 | 1.0559 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10873.145 | 0.9741 | 0.9583 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10873.145 | 0.9741 | 0.9583 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10873.145 | 0.9825 | 0.9718 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10873.145 | 0.9825 | 0.9718 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10873.145 | 0.9382 | 0.9001 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10873.145 | 0.9382 | 0.9001 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10873.145 | 0.4232 | 0.0028 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10873.145 | 0.4232 | 0.0028 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10873.145 | 0.0252 | -0.8959 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10873.145 | 0.0252 | -0.8959 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10873.145 | 0.0162 | -0.9268 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10873.145 | 0.0162 | -0.9268 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10873.145 | 0.0218 | -0.9075 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10873.145 | 0.0218 | -0.9075 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10873.145 | 0.0174 | -0.9226 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10873.145 | 0.0174 | -0.9226 | 1.2454 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12400.17 | 0.9903 | 0.9838 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12400.17 | 0.9903 | 0.9838 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12400.17 | 0.9560 | 0.9263 | 1.1992 |