Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12400.17 | 0.9560 | 0.9263 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12400.17 | 0.9884 | 0.9806 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12400.17 | 0.9884 | 0.9806 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12400.17 | 0.9463 | 0.9101 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12400.17 | 0.9463 | 0.9101 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12400.17 | 0.5091 | 0.1391 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12400.17 | 0.5091 | 0.1391 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12400.17 | 0.0218 | -0.9177 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12400.17 | 0.0218 | -0.9177 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12400.17 | 0.0186 | -0.9278 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12400.17 | 0.0186 | -0.9278 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12400.17 | 0.0220 | -0.9170 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12400.17 | 0.0220 | -0.9170 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12400.17 | 0.0246 | -0.9091 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12400.17 | 0.0246 | -0.9091 | 1.1992 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14257.189 | 0.9576 | 0.7830 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14257.189 | 0.9576 | 0.7830 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14257.189 | 0.9467 | 0.7297 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14257.189 | 0.9467 | 0.7297 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14257.189 | 0.9300 | 0.6504 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14257.189 | 0.9300 | 0.6504 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14257.189 | 0.9717 | 0.8536 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14257.189 | 0.9717 | 0.8536 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14257.189 | 0.7690 | -0.0025 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14257.189 | 0.7690 | -0.0025 | 0.3775 |