Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14257.189 | 0.0112 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14257.189 | 0.0112 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14257.189 | 0.0103 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14257.189 | 0.0103 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14257.189 | 0.0099 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14257.189 | 0.0099 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14257.189 | 1.0162 | 1.0867 | 0.3775 | |
| HCC70 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14257.189 | 1.0162 | 1.0867 | 0.3775 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10694.145 | 1.0295 | 1.0257 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10694.145 | 1.0295 | 1.0257 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10694.145 | 0.9328 | 0.9397 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10694.145 | 0.9328 | 0.9397 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10694.145 | 1.0129 | 1.0113 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10694.145 | 1.0129 | 1.0113 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10694.145 | 0.9494 | 0.9548 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10694.145 | 0.9494 | 0.9548 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10694.145 | 0.9018 | 0.9111 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10694.145 | 0.9018 | 0.9111 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10694.145 | 0.0481 | -0.4738 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10694.145 | 0.0481 | -0.4738 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10694.145 | 0.0085 | -0.7546 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10694.145 | 0.0085 | -0.7546 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10694.145 | 0.0092 | -0.7462 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10694.145 | 0.0092 | -0.7462 | 2.2732 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10694.145 | 0.0054 | -0.7988 | 2.2732 |