Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
SK-BR-3
HER2amp
Luminal
Nelfinavir
33.3
uM
12999.174
0.2053 -0.7021 0.8315
SUM149PT
TNBC
Basal B
Nelfinavir
0.0000853
uM
13123.174
1.1000 1.1917 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
0.000427
uM
13123.174
1.0491 1.0942 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
0.00213
uM
13123.174
0.9675 0.9375 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
0.0107
uM
13123.174
1.1486 1.2848 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
0.0533
uM
13123.174
1.0836 1.1605 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
0.267
uM
13123.174
1.0315 1.0605 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
1.33
uM
13123.174
0.9922 0.9849 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
6.67
uM
13123.174
0.9268 0.8591 1.0408
SUM149PT
TNBC
Basal B
Nelfinavir
33.3
uM
13123.174
0.0029 -0.9926 1.0408
SUM159PT
TNBC
Basal B
Nelfinavir
0.0000853
uM
13004.174
0.9823 0.9891 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
0.000427
uM
13004.174
0.8396 0.8961 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
0.00213
uM
13004.174
0.8286 0.8885 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
0.0107
uM
13004.174
0.9571 0.9734 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
0.0533
uM
13004.174
0.9426 0.9642 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
0.267
uM
13004.174
0.9149 0.9465 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
1.33
uM
13004.174
0.8859 0.9274 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
6.67
uM
13004.174
0.6761 0.7747 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
33.3
uM
13004.174
0.0019 -0.7031 3.2757
SUM159PT
TNBC
Basal B
Nelfinavir
0.0000853
uM
13054.174
1.0305 1.0194 3.1161
SUM159PT
TNBC
Basal B
Nelfinavir
0.000427
uM
13054.174
0.9013 0.9344 3.1161
SUM159PT
TNBC
Basal B
Nelfinavir
0.00213
uM
13054.174
0.9317 0.9551 3.1161
SUM159PT
TNBC
Basal B
Nelfinavir
0.0107
uM
13054.174
0.9647 0.9771 3.1161
SUM159PT
TNBC
Basal B
Nelfinavir
0.0533
uM
13054.174
0.9640 0.9766 3.1161
SUM159PT
TNBC
Basal B
Nelfinavir
0.267
uM
13054.174
0.9188 0.9464 3.1161