Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11849.145 | 0.0180 | -0.8564 | 1.5253 | |
| HCC1937 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11849.145 | 0.0180 | -0.8564 | 1.5253 | |
| HCC1937 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11849.145 | 0.0209 | -0.8417 | 1.5253 | |
| HCC1937 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11849.145 | 0.0209 | -0.8417 | 1.5253 | |
| HCC1937 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11849.145 | 0.0159 | -0.8677 | 1.5253 | |
| HCC1937 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11849.145 | 0.0159 | -0.8677 | 1.5253 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11055.145 | 1.0303 | 1.0342 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11055.145 | 1.0303 | 1.0342 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11055.145 | 0.9605 | 0.9547 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11055.145 | 0.9605 | 0.9547 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11055.145 | 0.9911 | 0.9898 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11055.145 | 0.9911 | 0.9898 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11055.145 | 0.9730 | 0.9692 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11055.145 | 0.9730 | 0.9692 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11055.145 | 0.9474 | 0.9396 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11055.145 | 0.9474 | 0.9396 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11055.145 | 0.0582 | -0.6021 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11055.145 | 0.0582 | -0.6021 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11055.145 | 0.1435 | -0.3356 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11055.145 | 0.1435 | -0.3356 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11055.145 | 0.0983 | -0.4642 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11055.145 | 0.0983 | -0.4642 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11055.145 | 0.0430 | -0.6650 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11055.145 | 0.0430 | -0.6650 | 1.7616 | |
| HCC1954 | HER2amp | Basal A | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14209.189 | 0.9493 | 0.9490 | 2.0117 |