Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14212.189 | 0.9550 | 0.9442 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14212.189 | 1.0160 | 1.0196 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14212.189 | 1.0160 | 1.0196 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14212.189 | 0.1106 | -0.4838 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14212.189 | 0.1106 | -0.4838 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14212.189 | 0.0004 | -0.9835 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14212.189 | 0.0004 | -0.9835 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14212.189 | 0.6165 | 0.4852 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14212.189 | 0.6165 | 0.4852 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14212.189 | 0.9974 | 0.9968 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14212.189 | 0.9974 | 0.9968 | 1.6254 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14616.189 | 0.9994 | 0.9992 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14616.189 | 0.9994 | 0.9992 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14616.189 | 0.8952 | 0.8506 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14616.189 | 0.8952 | 0.8506 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14616.189 | 1.0432 | 1.0603 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14616.189 | 1.0432 | 1.0603 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14616.189 | 0.9897 | 0.9855 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14616.189 | 0.9897 | 0.9855 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14616.189 | 0.9731 | 0.9621 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14616.189 | 0.9731 | 0.9621 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14616.189 | 0.0874 | -0.6380 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14616.189 | 0.0874 | -0.6380 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14616.189 | 0.0026 | -0.9694 | 1.4258 | |
| HCC38 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14616.189 | 0.0026 | -0.9694 | 1.4258 |