Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Mebendazole | 0.533 | uM | 13130.174 | 0.8390 | 0.4202 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Mebendazole | 2.67 | uM | 13130.174 | 0.8826 | 0.5675 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Mebendazole | 13.3 | uM | 13130.174 | 0.7966 | 0.2836 | 0.5126 | |||
| BT-483 | HR+ | Luminal | Mebendazole | 66.7 | uM | 13130.174 | 0.8133 | 0.3364 | 0.5126 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 0.000171 | uM | 12690.174 | 0.9882 | 0.9903 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 0.000853 | uM | 12690.174 | 0.9625 | 0.9689 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 0.00427 | uM | 12690.174 | 0.9821 | 0.9852 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 0.0213 | uM | 12690.174 | 0.9595 | 0.9664 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 0.107 | uM | 12690.174 | 0.9905 | 0.9922 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 0.533 | uM | 12690.174 | 0.4889 | 0.4912 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 2.67 | uM | 12690.174 | 0.3713 | 0.3321 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 13.3 | uM | 12690.174 | 0.3297 | 0.2687 | 2.4378 | |||
| BT-549 | TNBC | Basal B | Mebendazole | 66.7 | uM | 12690.174 | 0.3283 | 0.2665 | 2.4378 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 0.000171 | uM | 12647.174 | 0.9235 | 0.8370 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 0.000853 | uM | 12647.174 | 0.9320 | 0.8550 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 0.00427 | uM | 12647.174 | 0.9167 | 0.8224 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 0.0213 | uM | 12647.174 | 0.8852 | 0.7557 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 0.107 | uM | 12647.174 | 0.9348 | 0.8610 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 0.533 | uM | 12647.174 | 0.6460 | 0.2541 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 2.67 | uM | 12647.174 | 0.4587 | -0.1302 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 13.3 | uM | 12647.174 | 0.5069 | -0.0321 | 0.9362 | |||
| CAMA-1 | HR+ | Luminal | Mebendazole | 66.7 | uM | 12647.174 | 0.4620 | -0.1234 | 0.9362 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 0.000171 | uM | 13099.174 | 1.0288 | 1.0611 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 0.000853 | uM | 13099.174 | 0.9429 | 0.8792 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 0.00427 | uM | 13099.174 | 0.9497 | 0.8937 | 0.9441 |