Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.000853 | uM | 12964.174 | 0.9226 | 0.8057 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.00427 | uM | 12964.174 | 0.9868 | 0.9666 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.0213 | uM | 12964.174 | 0.9787 | 0.9462 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.107 | uM | 12964.174 | 0.9316 | 0.8281 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.533 | uM | 12964.174 | 0.5847 | 0.0127 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 2.67 | uM | 12964.174 | 0.5437 | -0.0767 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 13.3 | uM | 12964.174 | 0.3854 | -0.4032 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 66.7 | uM | 12964.174 | 0.4213 | -0.3317 | 0.7885 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.000171 | uM | 13562.174 | 0.9964 | 0.9899 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.000853 | uM | 13562.174 | 0.9504 | 0.8638 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.00427 | uM | 13562.174 | 1.0143 | 1.0398 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.0213 | uM | 13562.174 | 0.9754 | 0.9321 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.107 | uM | 13562.174 | 0.8133 | 0.5022 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 0.533 | uM | 13562.174 | 0.5121 | -0.2085 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 2.67 | uM | 13562.174 | 0.5475 | -0.1318 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 13.3 | uM | 13562.174 | 0.4975 | -0.2396 | 0.7219 | |||
| MDA-MB-453 | TNBC | Luminal | Mebendazole | 66.7 | uM | 13562.174 | 0.4416 | -0.3553 | 0.7219 | |||
| MX1 | Unknown | Unknown | Mebendazole | 0.000171 | uM | 12667.174 | 0.9958 | 0.9897 | 0.8129 | |||
| MX1 | Unknown | Unknown | Mebendazole | 0.000853 | uM | 12667.174 | 0.9954 | 0.9888 | 0.8129 | |||
| MX1 | Unknown | Unknown | Mebendazole | 0.00427 | uM | 12667.174 | 1.0266 | 1.0655 | 0.8129 | |||
| MX1 | Unknown | Unknown | Mebendazole | 0.0213 | uM | 12667.174 | 1.0049 | 1.0121 | 0.8129 | |||
| MX1 | Unknown | Unknown | Mebendazole | 0.107 | uM | 12667.174 | 0.9851 | 0.9634 | 0.8129 | |||
| MX1 | Unknown | Unknown | Mebendazole | 0.533 | uM | 12667.174 | 0.6434 | 0.1626 | 0.8129 | |||
| MX1 | Unknown | Unknown | Mebendazole | 2.67 | uM | 12667.174 | 0.5097 | -0.1271 | 0.8129 | |||
| MX1 | Unknown | Unknown | Mebendazole | 13.3 | uM | 12667.174 | 0.4431 | -0.2652 | 0.8129 |