Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Mebendazole | 0.0213 | uM | 13099.174 | 0.9502 | 0.8947 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 0.107 | uM | 13099.174 | 0.9354 | 0.8634 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 0.533 | uM | 13099.174 | 0.8013 | 0.5818 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 2.67 | uM | 13099.174 | 0.6137 | 0.1925 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 13.3 | uM | 13099.174 | 0.5953 | 0.1545 | 0.9441 | |||
| HCC1143 | TNBC | Basal A | Mebendazole | 66.7 | uM | 13099.174 | 0.4206 | -0.2007 | 0.9441 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 0.000171 | uM | 12696.174 | 0.9819 | 0.9429 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 0.000853 | uM | 12696.174 | 0.9080 | 0.7159 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 0.00427 | uM | 12696.174 | 0.9458 | 0.8306 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 0.0213 | uM | 12696.174 | 0.9059 | 0.7096 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 0.107 | uM | 12696.174 | 0.9318 | 0.7878 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 0.533 | uM | 12696.174 | 0.3372 | -0.6439 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 2.67 | uM | 12696.174 | 0.1949 | -0.8508 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 13.3 | uM | 12696.174 | 0.0812 | -0.9628 | 0.6299 | |||
| HCC1187 | TNBC | Basal A | Mebendazole | 66.7 | uM | 12696.174 | 0.0312 | -0.9919 | 0.6299 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 0.000171 | uM | 13538.174 | 1.0145 | 1.0632 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 0.000853 | uM | 13538.174 | 0.9558 | 0.8132 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 0.00427 | uM | 13538.174 | 0.9950 | 0.9785 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 0.0213 | uM | 13538.174 | 0.9630 | 0.8432 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 0.107 | uM | 13538.174 | 0.9792 | 0.9109 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 0.533 | uM | 13538.174 | 0.7434 | 0.0519 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 2.67 | uM | 13538.174 | 0.8091 | 0.2637 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 13.3 | uM | 13538.174 | 0.6268 | -0.2732 | 0.4615 | |||
| HCC1395 | TNBC | Basal B | Mebendazole | 66.7 | uM | 13538.174 | 0.4191 | -0.6961 | 0.4615 | |||
| HCC1419 | HER2amp | Luminal | Mebendazole | 0.000171 | uM | 12612.174 | 0.9589 | 0.8640 | 0.5962 |