Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Mebendazole | 66.7 | uM | 12667.174 | 0.3945 | -0.3630 | 0.8129 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 0.000171 | uM | 12999.174 | 0.9967 | 0.9920 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 0.000853 | uM | 12999.174 | 0.9738 | 0.9371 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 0.00427 | uM | 12999.174 | 1.0162 | 1.0390 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 0.0213 | uM | 12999.174 | 0.9606 | 0.9056 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 0.107 | uM | 12999.174 | 0.9664 | 0.9196 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 0.533 | uM | 12999.174 | 0.6491 | 0.1892 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 2.67 | uM | 12999.174 | 0.4178 | -0.3000 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 13.3 | uM | 12999.174 | 0.3087 | -0.5134 | 0.8315 | |||
| SK-BR-3 | HER2amp | Luminal | Mebendazole | 66.7 | uM | 12999.174 | 0.2956 | -0.5382 | 0.8315 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 0.000171 | uM | 13123.174 | 1.1024 | 1.1964 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 0.000853 | uM | 13123.174 | 0.9668 | 0.9361 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 0.00427 | uM | 13123.174 | 1.0412 | 1.0791 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 0.0213 | uM | 13123.174 | 1.1220 | 1.2340 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 0.107 | uM | 13123.174 | 0.9182 | 0.8426 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 0.533 | uM | 13123.174 | 0.7270 | 0.4723 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 2.67 | uM | 13123.174 | 0.5319 | 0.0904 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 13.3 | uM | 13123.174 | 0.2813 | -0.4087 | 1.0408 | |||
| SUM149PT | TNBC | Basal B | Mebendazole | 66.7 | uM | 13123.174 | 0.2328 | -0.5069 | 1.0408 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.000171 | uM | 13004.174 | 1.0134 | 1.0082 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.000853 | uM | 13004.174 | 0.8128 | 0.8774 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.00427 | uM | 13004.174 | 0.9394 | 0.9622 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.0213 | uM | 13004.174 | 0.8881 | 0.9289 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.107 | uM | 13004.174 | 0.6875 | 0.7838 | 3.2757 | |||
| SUM159PT | TNBC | Basal B | Mebendazole | 0.533 | uM | 13004.174 | 0.2055 | 0.2338 | 3.2757 |