Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.0000853 | uM | 10580.137 | 0.9771 | 0.9465 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.000427 | uM | 10580.137 | 0.8946 | 0.7553 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.00213 | uM | 10580.137 | 0.9415 | 0.8636 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.0107 | uM | 10580.137 | 0.9306 | 0.8384 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.0533 | uM | 10580.137 | 0.9437 | 0.8687 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.267 | uM | 10580.137 | 0.8748 | 0.7098 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 1.33 | uM | 10580.137 | 0.9238 | 0.8227 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 6.67 | uM | 10580.137 | 0.8336 | 0.6159 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 33.3 | uM | 10580.137 | 0.7073 | 0.3329 | 0.8535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.0000853 | uM | 10754.149 | 0.9728 | 0.9597 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.000427 | uM | 10754.149 | 0.9265 | 0.8903 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.00213 | uM | 10754.149 | 0.9966 | 0.9950 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.0107 | uM | 10754.149 | 1.0008 | 1.0013 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.0533 | uM | 10754.149 | 0.9715 | 0.9578 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.267 | uM | 10754.149 | 0.9669 | 0.9508 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 1.33 | uM | 10754.149 | 0.9218 | 0.8833 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 6.67 | uM | 10754.149 | 0.7370 | 0.5963 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 33.3 | uM | 10754.149 | 0.5993 | 0.3701 | 1.3535 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.000128 | uM | 11938.161 | 0.9309 | 0.8152 | 0.7388 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.00064 | uM | 11938.161 | 0.8303 | 0.5548 | 0.7388 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.0032 | uM | 11938.161 | 0.9831 | 0.9544 | 0.7388 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.016 | uM | 11938.161 | 0.9560 | 0.8817 | 0.7388 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.08 | uM | 11938.161 | 0.9118 | 0.7651 | 0.7388 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 0.4 | uM | 11938.161 | 0.9427 | 0.8464 | 0.7388 | |
| UACC-812 | HER2amp | Luminal | L-779450 | BRAF | MAPK | 2 | uM | 11938.161 | 0.8418 | 0.5842 | 0.7388 |