Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | L-779450 | BRAF | MAPK | 33.3 | uM | 12428.166 | 0.6740 | 0.2378 | 0.8223 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.0000853 | uM | 10819.149 | 1.0238 | 1.0231 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.000427 | uM | 10819.149 | 0.9462 | 0.9468 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.00213 | uM | 10819.149 | 1.0133 | 1.0130 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.0107 | uM | 10819.149 | 0.9847 | 0.9850 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.0533 | uM | 10819.149 | 1.1163 | 1.1103 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.267 | uM | 10819.149 | 1.0667 | 1.0640 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 1.33 | uM | 10819.149 | 1.0675 | 1.0648 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 6.67 | uM | 10819.149 | 0.8848 | 0.8841 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 33.3 | uM | 10819.149 | 0.2938 | 0.1005 | 2.0505 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.000128 | uM | 11937.161 | 0.9340 | 0.9451 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.00064 | uM | 11937.161 | 0.9334 | 0.9445 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.0032 | uM | 11937.161 | 0.9203 | 0.9333 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.016 | uM | 11937.161 | 1.0046 | 1.0037 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.08 | uM | 11937.161 | 0.9442 | 0.9537 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.4 | uM | 11937.161 | 0.9640 | 0.9703 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 2 | uM | 11937.161 | 0.8262 | 0.8502 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 10 | uM | 11937.161 | 0.4410 | 0.4322 | 2.4516 | |
| SUM149PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 50 | uM | 11937.161 | 0.0070 | -0.7351 | 2.4516 | |
| SUM159PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.0000853 | uM | 10520.137 | 1.0977 | 1.0499 | 3.7823 | |
| SUM159PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.000427 | uM | 10520.137 | 0.7854 | 0.8763 | 3.7823 | |
| SUM159PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.00213 | uM | 10520.137 | 0.7762 | 0.8704 | 3.7823 | |
| SUM159PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.0107 | uM | 10520.137 | 0.7928 | 0.8809 | 3.7823 | |
| SUM159PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.0533 | uM | 10520.137 | 0.9228 | 0.9580 | 3.7823 | |
| SUM159PT | TNBC | Basal B | L-779450 | BRAF | MAPK | 0.267 | uM | 10520.137 | 0.7288 | 0.8395 | 3.7823 |