Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Mebendazole | 2.67 | uM | 13546.174 | 0.4843 | 0.0950 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 13.3 | uM | 13546.174 | 0.3305 | -0.2029 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 66.7 | uM | 13546.174 | 0.2547 | -0.3581 | 1.2035 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 0.000171 | uM | 13135.174 | 0.9195 | 0.7049 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 0.000853 | uM | 13135.174 | 0.9295 | 0.7404 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 0.00427 | uM | 13135.174 | 0.9363 | 0.7647 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 0.0213 | uM | 13135.174 | 0.9593 | 0.8478 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 0.107 | uM | 13135.174 | 0.9044 | 0.6519 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 0.533 | uM | 13135.174 | 0.7024 | 0.0212 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 2.67 | uM | 13135.174 | 0.6660 | -0.0770 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 13.3 | uM | 13135.174 | 0.6191 | -0.1968 | 0.5256 | |||
| HCC202 | HER2amp | Luminal | Mebendazole | 66.7 | uM | 13135.174 | 0.6604 | -0.0918 | 0.5256 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.000171 | uM | 12939.174 | 0.9956 | 0.9747 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.000853 | uM | 12939.174 | 0.9193 | 0.5689 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.00427 | uM | 12939.174 | 0.9946 | 0.9692 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.0213 | uM | 12939.174 | 0.9753 | 0.8607 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.107 | uM | 12939.174 | 0.9057 | 0.5030 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.533 | uM | 12939.174 | 0.7903 | 0.0142 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 2.67 | uM | 12939.174 | 0.6465 | -0.4318 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 13.3 | uM | 12939.174 | 0.5558 | -0.6327 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 66.7 | uM | 12939.174 | 0.3937 | -0.8642 | 0.3466 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.000171 | uM | 13583.174 | 1.0127 | 1.0705 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.000853 | uM | 13583.174 | 0.9581 | 0.7790 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.00427 | uM | 13583.174 | 1.0207 | 1.1156 | 0.3654 | |||
| HCC3153 | TNBC | Basal A | Mebendazole | 0.0213 | uM | 13583.174 | 1.0232 | 1.1296 | 0.3654 |