Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Mebendazole | 66.7 | uM | 13038.174 | 0.5401 | 0.1984 | 1.2027 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 0.000171 | uM | 12702.174 | 0.9532 | 0.9489 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 0.000853 | uM | 12702.174 | 0.9259 | 0.9185 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 0.00427 | uM | 12702.174 | 0.9671 | 0.9642 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 0.0213 | uM | 12702.174 | 0.9744 | 0.9722 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 0.107 | uM | 12702.174 | 0.9178 | 0.9094 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 0.533 | uM | 12702.174 | 0.3635 | 0.1576 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 2.67 | uM | 12702.174 | 0.2425 | -0.0699 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 13.3 | uM | 12702.174 | 0.2175 | -0.1231 | 1.8506 | |||
| HCC1806 | TNBC | Basal A | Mebendazole | 66.7 | uM | 12702.174 | 0.1607 | -0.2552 | 1.8506 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 0.000171 | uM | 13115.174 | 0.9922 | 0.9809 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 0.000853 | uM | 13115.174 | 0.9966 | 0.9916 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 0.00427 | uM | 13115.174 | 0.9892 | 0.9734 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 0.0213 | uM | 13115.174 | 1.0047 | 1.0116 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 0.107 | uM | 13115.174 | 0.9855 | 0.9644 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 0.533 | uM | 13115.174 | 0.9938 | 0.9847 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 2.67 | uM | 13115.174 | 0.8190 | 0.5641 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 13.3 | uM | 13115.174 | 0.8135 | 0.5513 | 0.8122 | |||
| HCC1937 | TNBC | Basal A | Mebendazole | 66.7 | uM | 13115.174 | 0.7030 | 0.2960 | 0.8122 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 0.000171 | uM | 13546.174 | 0.9478 | 0.9128 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 0.000853 | uM | 13546.174 | 0.8360 | 0.7234 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 0.00427 | uM | 13546.174 | 1.1015 | 1.1672 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 0.0213 | uM | 13546.174 | 0.9278 | 0.8793 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 0.107 | uM | 13546.174 | 0.7672 | 0.6048 | 1.2035 | |||
| HCC1954 | HER2amp | Basal A | Mebendazole | 0.533 | uM | 13546.174 | 0.4525 | 0.0348 | 1.2035 |