Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10695.144 | 0.2641 | -0.3205 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10695.144 | 0.2828 | -0.2818 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10695.144 | 0.3219 | -0.2023 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11852.144 | 1.0225 | 1.0349 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11852.144 | 1.0005 | 1.0007 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11852.144 | 1.1328 | 1.2034 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11852.144 | 1.0725 | 1.1118 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11852.144 | 1.0548 | 1.0846 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11852.144 | 0.6738 | 0.4718 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11852.144 | 0.5496 | 0.2564 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11852.144 | 1.0018 | 1.0029 | 1.2876 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 11852.144 | 0.3626 | -0.0903 | 1.2876 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10939.144 | 0.9661 | 0.9601 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10939.144 | 0.9422 | 0.9317 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10939.144 | 0.9876 | 0.9854 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10939.144 | 0.9561 | 0.9482 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10939.144 | 0.9356 | 0.9237 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10939.144 | 0.9832 | 0.9803 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10939.144 | 0.5066 | 0.3442 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10939.144 | 0.7839 | 0.7349 | 1.7115 | |
| T47D | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10939.144 | 0.7600 | 0.7037 | 1.7115 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12608.168 | 1.0019 | 1.0036 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12608.168 | 0.9620 | 0.9274 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12608.168 | 1.0108 | 1.0205 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12608.168 | 0.9992 | 0.9984 | 1.0486 |