Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 10579.144 | 0.6782 | 0.3332 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12098.144 | 0.9879 | 0.9797 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12098.144 | 1.0574 | 1.0955 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12098.144 | 1.0430 | 1.0716 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12098.144 | 1.0201 | 1.0336 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12098.144 | 0.9766 | 0.9608 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12098.144 | 1.0461 | 1.0768 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12098.144 | 0.5304 | 0.1770 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12098.144 | 0.9215 | 0.8678 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 133 | uM | 12098.144 | 0.8924 | 0.8183 | 1.1959 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11058.144 | 0.9849 | 0.9856 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11058.144 | 1.0403 | 1.0376 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11058.144 | 1.0062 | 1.0059 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11058.144 | 1.0121 | 1.0114 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11058.144 | 0.7702 | 0.7679 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11058.144 | 0.6025 | 0.5743 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11058.144 | 0.5593 | 0.5199 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11058.144 | 0.6517 | 0.6338 | 2.1171 | |
| SUM229PE | TNBC | - | JNK-IN-5A | JNK | JNK | 133 | uM | 11058.144 | 0.3483 | 0.2152 | 2.1171 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10695.144 | 1.0578 | 1.0933 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10695.144 | 1.0506 | 1.0817 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10695.144 | 1.0026 | 1.0042 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10695.144 | 1.0170 | 1.0275 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10695.144 | 0.9941 | 0.9905 | 1.2333 | |
| SUM52PE | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10695.144 | 0.2684 | -0.3117 | 1.2333 |