Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11057.144 | 1.0819 | 1.0421 | 3.7784 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11057.144 | 1.0693 | 1.0358 | 3.7784 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11057.144 | 1.0616 | 1.0319 | 3.7784 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11057.144 | 0.7085 | 0.8257 | 3.7784 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11057.144 | 0.4844 | 0.6509 | 3.7784 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11057.144 | 0.3402 | 0.5035 | 3.7784 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11057.144 | 0.6128 | 0.7569 | 3.7784 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 11057.144 | 0.0448 | -0.1209 | 3.7784 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12269.144 | 1.0341 | 1.0667 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12269.144 | 0.9504 | 0.9032 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12269.144 | 0.7223 | 0.4557 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12269.144 | 0.9749 | 0.9510 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12269.144 | 0.9443 | 0.8911 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12269.144 | 0.7722 | 0.5537 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12269.144 | 0.8213 | 0.6503 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12269.144 | 1.0205 | 1.0401 | 1.0241 | |
| SUM185PE | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 12269.144 | 0.3702 | -0.2421 | 1.0241 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10579.144 | 1.0549 | 1.1147 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10579.144 | 0.9395 | 0.8739 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10579.144 | 1.0437 | 1.0914 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10579.144 | 1.0318 | 1.0664 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10579.144 | 1.1569 | 1.3289 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10579.144 | 0.9697 | 0.9367 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10579.144 | 0.6478 | 0.2710 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10579.144 | 0.6668 | 0.3098 | 0.9576 |