Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12428.168 | 1.0218 | 1.0550 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12428.168 | 0.9997 | 0.9992 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12428.168 | 0.4756 | -0.2141 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 8 | uM | 12428.168 | 0.1737 | -0.7783 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 40 | uM | 12428.168 | 0.4199 | -0.3279 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 200 | uM | 12428.168 | 0.1866 | -0.7574 | 0.7957 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10819.144 | 0.9535 | 0.9579 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10819.144 | 0.9014 | 0.9092 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10819.144 | 0.9664 | 0.9696 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10819.144 | 0.9176 | 0.9245 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10819.144 | 0.9196 | 0.9263 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10819.144 | 0.8686 | 0.8778 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10819.144 | 0.2401 | 0.0561 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10819.144 | 0.2496 | 0.0746 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 10819.144 | 0.3480 | 0.2470 | 2.2343 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11937.144 | 0.9855 | 0.9880 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11937.144 | 0.9688 | 0.9741 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11937.144 | 0.9909 | 0.9925 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11937.144 | 1.0814 | 1.0655 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11937.144 | 0.9716 | 0.9764 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11937.144 | 0.9764 | 0.9804 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11937.144 | 0.1508 | -0.0820 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11937.144 | 0.5168 | 0.5241 | 2.4293 | |
| SUM149PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 11937.144 | 0.1639 | -0.0499 | 2.4293 | |
| SUM159PT | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11057.144 | 1.0661 | 1.0342 | 3.7784 |