Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12220.144 | 0.8916 | 0.5990 | 0.5126 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12220.144 | 0.6214 | -0.2096 | 0.5126 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12220.144 | 0.8540 | 0.4700 | 0.5126 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 133 | uM | 12220.144 | 0.3784 | -0.6997 | 0.5126 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11851.144 | 0.9889 | 0.9838 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11851.144 | 0.9018 | 0.8548 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11851.144 | 0.9476 | 0.9230 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11851.144 | 0.9401 | 0.9119 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11851.144 | 0.9412 | 0.9136 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11851.144 | 0.7847 | 0.6759 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11851.144 | 0.3548 | -0.0605 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11851.144 | 0.9665 | 0.9509 | 1.3716 | |
| SK-BR-3 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 11851.144 | 0.0990 | -0.6295 | 1.3716 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10875.144 | 0.9977 | 0.9940 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10875.144 | 1.0205 | 1.0529 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10875.144 | 0.9891 | 0.9721 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10875.144 | 1.0524 | 1.1357 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10875.144 | 0.9890 | 0.9718 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10875.144 | 0.4842 | -0.2123 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10875.144 | 0.1137 | -0.8775 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10875.144 | 0.2742 | -0.6206 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 133 | uM | 10875.144 | 0.1726 | -0.7907 | 0.7785 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12428.168 | 1.0411 | 1.1038 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12428.168 | 1.0135 | 1.0339 | 0.7957 | |
| SUM1315MO2 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12428.168 | 1.0091 | 1.0229 | 0.7957 |