Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 40 | uM | 12414.168 | 0.5462 | 0.2116 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 200 | uM | 12414.168 | 0.1894 | -0.4961 | 1.2069 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10644.144 | 1.0353 | 1.1340 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10644.144 | 0.8916 | 0.6145 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10644.144 | 0.9999 | 0.9997 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10644.144 | 0.9335 | 0.7589 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10644.144 | 1.0222 | 1.0839 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10644.144 | 0.4982 | -0.4554 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10644.144 | 0.1675 | -0.9288 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10644.144 | 0.3476 | -0.7219 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 133 | uM | 10644.144 | 0.2175 | -0.8841 | 0.5357 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10874.144 | 1.0653 | 1.1815 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10874.144 | 1.0736 | 1.2050 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10874.144 | 1.0395 | 1.1093 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10874.144 | 1.1147 | 1.3216 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10874.144 | 1.0040 | 1.0111 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10874.144 | 0.9107 | 0.7589 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10874.144 | 0.1922 | -0.7923 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10874.144 | 0.5321 | -0.1590 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 133 | uM | 10874.144 | 0.4189 | -0.3945 | 0.7282 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12220.144 | 0.8900 | 0.5933 | 0.5126 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12220.144 | 0.9069 | 0.6530 | 0.5126 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12220.144 | 0.9663 | 0.8706 | 0.5126 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12220.144 | 0.9282 | 0.7294 | 0.5126 | |
| MX1 | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12220.144 | 0.8882 | 0.5869 | 0.5126 |