Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10938.144 | 0.8812 | 0.7895 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10938.144 | 0.5237 | 0.1323 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10938.144 | 0.9564 | 0.9231 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10938.144 | 0.8968 | 0.8174 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10938.144 | 0.8632 | 0.7572 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10938.144 | 0.8994 | 0.8218 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10938.144 | 0.4602 | 0.0107 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10938.144 | 0.7729 | 0.5944 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10938.144 | 0.6860 | 0.4357 | 1.1369 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12333.168 | 1.0228 | 1.0791 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12333.168 | 1.0682 | 1.2403 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12333.168 | 1.0491 | 1.1720 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12333.168 | 0.9213 | 0.7371 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12333.168 | 0.9210 | 0.7360 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12333.168 | 0.5961 | -0.1785 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 8 | uM | 12333.168 | 0.5621 | -0.2574 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 40 | uM | 12333.168 | 0.6494 | -0.0482 | 0.5815 | |
| MDA-MB-415 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 200 | uM | 12333.168 | 0.6645 | -0.0098 | 0.5815 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12414.168 | 0.9532 | 0.9221 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12414.168 | 0.9275 | 0.8791 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12414.168 | 1.0095 | 1.0157 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12414.168 | 0.9719 | 0.9532 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12414.168 | 0.9756 | 0.9596 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12414.168 | 0.5147 | 0.1536 | 1.2069 | |
| MDA-MB-453 | TNBC | Luminal | JNK-IN-5A | JNK | JNK | 8 | uM | 12414.168 | 0.2115 | -0.4479 | 1.2069 |