Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10643.144 | 0.9741 | 0.9282 | 0.7178 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10643.144 | 0.9659 | 0.9057 | 0.7178 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10643.144 | 0.9941 | 0.9835 | 0.7178 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10643.144 | 0.8813 | 0.6772 | 0.7178 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10643.144 | 0.5265 | -0.1818 | 0.7178 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10643.144 | 0.6380 | 0.0693 | 0.7178 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10643.144 | 0.5227 | -0.1900 | 0.7178 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10999.144 | 1.0718 | 1.2119 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10999.144 | 1.0491 | 1.1444 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10999.144 | 1.0572 | 1.1685 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10999.144 | 1.0300 | 1.0878 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10999.144 | 0.9894 | 0.9693 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10999.144 | 1.0572 | 1.1685 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10999.144 | 0.5228 | -0.2207 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10999.144 | 1.0872 | 1.2585 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10999.144 | 1.0936 | 1.2778 | 0.6880 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12379.168 | 1.0557 | 1.2459 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12379.168 | 1.1013 | 1.4589 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12379.168 | 1.0695 | 1.3095 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12379.168 | 1.0073 | 1.0316 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12379.168 | 1.0507 | 1.2234 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12379.168 | 1.0634 | 1.2815 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 8 | uM | 12379.168 | 1.0077 | 1.0329 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 40 | uM | 12379.168 | 1.0617 | 1.2736 | 0.4672 | |
| MDA-MB-361 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 200 | uM | 12379.168 | 0.5188 | -0.5091 | 0.4672 |