Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 20 | uM | 10473.142 | 0.1812 | -0.5879 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 100 | uM | 10473.142 | 0.0071 | -0.9793 | 1.0815 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 10755.154 | 0.9635 | 0.9283 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 10755.154 | 0.8941 | 0.7922 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 10755.154 | 0.9103 | 0.8239 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10755.154 | 0.9065 | 0.8165 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10755.154 | 0.9991 | 0.9983 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10755.154 | 0.8432 | 0.6921 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10755.154 | 0.9058 | 0.8150 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10755.154 | 0.5590 | 0.1307 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10755.154 | 0.0133 | -0.9711 | 1.0198 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 12070.154 | 0.9681 | 0.9419 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 12070.154 | 1.0588 | 1.1066 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 12070.154 | 0.9764 | 0.9570 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 12070.154 | 0.9985 | 0.9973 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 12070.154 | 0.9203 | 0.8546 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 12070.154 | 0.5957 | 0.2492 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 12070.154 | 0.8160 | 0.6626 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 12070.154 | 0.2760 | -0.3791 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 12070.154 | 0.0181 | -0.9477 | 1.1006 | |
| HCC1143 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 12112.154 | 0.8979 | 0.8858 | 1.8321 | |
| HCC1143 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 12112.154 | 0.9817 | 0.9799 | 1.8321 | |
| HCC1143 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 12112.154 | 0.9168 | 0.9074 | 1.8321 | |
| HCC1143 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 12112.154 | 0.9732 | 0.9706 | 1.8321 | |
| HCC1143 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 12112.154 | 0.7799 | 0.7463 | 1.8321 |