Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14610.189 | 0.0165 | -0.9556 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14610.189 | 0.0165 | -0.9556 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14610.189 | 0.0184 | -0.9509 | 1.0787 | |
| 21NT | HER2amp | - | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14610.189 | 0.0184 | -0.9509 | 1.0787 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12224.145 | 1.0021 | 1.0043 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12224.145 | 1.0021 | 1.0043 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12224.145 | 1.0183 | 1.0376 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12224.145 | 1.0183 | 1.0376 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12224.145 | 1.0337 | 1.0693 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12224.145 | 1.0337 | 1.0693 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12224.145 | 0.9755 | 0.9497 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12224.145 | 0.9755 | 0.9497 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12224.145 | 1.0226 | 1.0465 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12224.145 | 1.0226 | 1.0465 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12224.145 | 0.6559 | 0.2970 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12224.145 | 0.6559 | 0.2970 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12224.145 | 0.0287 | -0.9479 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12224.145 | 0.0287 | -0.9479 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12224.145 | 0.0299 | -0.9456 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12224.145 | 0.0299 | -0.9456 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12224.145 | 0.0179 | -0.9678 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12224.145 | 0.0179 | -0.9678 | 0.9737 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14197.189 | 1.0077 | 1.0113 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14197.189 | 1.0077 | 1.0113 | 1.3593 | |
| 600MPE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14197.189 | 0.9374 | 0.9071 | 1.3593 |