Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12608.168 | 0.9893 | 0.9796 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12608.168 | 0.9893 | 0.9796 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 8 | uM | 12608.168 | 0.9983 | 0.9968 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 40 | uM | 12608.168 | 0.9821 | 0.9658 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | JNK-IN-5A | JNK | JNK | 200 | uM | 12608.168 | 1.0142 | 1.0270 | 1.0486 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10580.144 | 0.9814 | 0.9565 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10580.144 | 0.8724 | 0.7046 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10580.144 | 0.9364 | 0.8519 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10580.144 | 0.9770 | 0.9463 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10580.144 | 0.9554 | 0.8960 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10580.144 | 0.8816 | 0.7256 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10580.144 | 0.5984 | 0.0963 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10580.144 | 0.6092 | 0.1196 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10580.144 | 0.6054 | 0.1114 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10754.144 | 1.0625 | 1.1499 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10754.144 | 0.9606 | 0.9063 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10754.144 | 1.0674 | 1.1616 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10754.144 | 0.9788 | 0.9495 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 10754.144 | 1.0376 | 1.0900 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 10754.144 | 0.6304 | 0.1539 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10754.144 | 0.5939 | 0.0749 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10754.144 | 0.6376 | 0.1698 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10754.144 | 0.5933 | 0.0735 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11938.144 | 0.9741 | 0.9202 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11938.144 | 0.8253 | 0.4847 | 0.6445 |