Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0064 | uM | 10578.142 | 0.9453 | 0.9389 | 1.8112 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.032 | uM | 10578.142 | 0.9172 | 0.9068 | 1.8112 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.16 | uM | 10578.142 | 0.5406 | 0.4241 | 1.8112 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.8 | uM | 10578.142 | 0.1582 | -0.2774 | 1.8112 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 4 | uM | 10578.142 | 0.1177 | -0.3863 | 1.8112 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 20 | uM | 10578.142 | 0.0137 | -0.8127 | 1.8112 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 100 | uM | 10578.142 | 0.0040 | -0.9049 | 1.8112 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 11850.154 | 0.9586 | 0.9563 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 11850.154 | 0.9925 | 0.9922 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 11850.154 | 0.9269 | 0.9221 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 11850.154 | 1.0088 | 1.0092 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 11850.154 | 0.6520 | 0.5990 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 11850.154 | 0.1106 | -0.3680 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 11850.154 | 0.0757 | -0.4816 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 11850.154 | 0.0155 | -0.7739 | 1.9115 | |
| HCC38 | TNBC | Basal B | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 11850.154 | 0.0045 | -0.8817 | 1.9115 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 10873.154 | 1.0684 | 1.1170 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 10873.154 | 1.1380 | 1.2348 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 10873.154 | 0.9736 | 0.9545 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10873.154 | 0.9932 | 0.9882 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10873.154 | 0.8327 | 0.7092 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10873.154 | 0.7229 | 0.5137 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10873.154 | 0.4105 | -0.0687 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10873.154 | 0.1976 | -0.5030 | 1.1648 | |
| HCC70 | TNBC | Basal A | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10873.154 | 0.0116 | -0.9565 | 1.1648 |