Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12056.145 | 0.8812 | 0.7193 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12056.145 | 0.5077 | -0.1106 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12056.145 | 0.5077 | -0.1106 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12056.145 | 0.3512 | -0.4276 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12056.145 | 0.3512 | -0.4276 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12056.145 | 0.1218 | -0.8385 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12056.145 | 0.1218 | -0.8385 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12056.145 | 0.0896 | -0.8881 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12056.145 | 0.0896 | -0.8881 | 0.8365 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12178.145 | 0.9671 | 0.8936 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12178.145 | 0.9671 | 0.8936 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12178.145 | 1.0091 | 1.0298 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12178.145 | 1.0091 | 1.0298 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12178.145 | 0.9397 | 0.8070 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12178.145 | 0.9397 | 0.8070 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12178.145 | 1.0144 | 1.0473 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12178.145 | 1.0144 | 1.0473 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12178.145 | 0.9279 | 0.7702 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12178.145 | 0.9279 | 0.7702 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12178.145 | 0.6096 | -0.1084 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12178.145 | 0.6096 | -0.1084 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12178.145 | 0.3877 | -0.5741 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12178.145 | 0.3877 | -0.5741 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12178.145 | 0.1780 | -0.8805 | 0.6127 | |
| BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12178.145 | 0.1780 | -0.8805 | 0.6127 |