Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14230.189 | 0.9806 | 0.9174 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14230.189 | 0.9806 | 0.9174 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14230.189 | 1.0032 | 1.0139 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14230.189 | 1.0032 | 1.0139 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14230.189 | 1.0069 | 1.0300 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14230.189 | 1.0069 | 1.0300 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14230.189 | 0.9464 | 0.7759 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14230.189 | 0.9464 | 0.7759 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14230.189 | 0.2038 | -0.9353 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14230.189 | 0.2038 | -0.9353 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14230.189 | 0.0034 | -1.0000 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14230.189 | 0.0034 | -1.0000 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14230.189 | 0.0018 | -1.0000 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14230.189 | 0.0018 | -1.0000 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14230.189 | 1.0224 | 1.0977 | 0.4635 | |
BT-20 | TNBC | Basal A | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14230.189 | 1.0224 | 1.0977 | 0.4635 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12056.145 | 0.9691 | 0.9263 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12056.145 | 0.9691 | 0.9263 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12056.145 | 0.8671 | 0.6865 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12056.145 | 0.8671 | 0.6865 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12056.145 | 0.9280 | 0.8291 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12056.145 | 0.9280 | 0.8291 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12056.145 | 0.9285 | 0.8303 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12056.145 | 0.9285 | 0.8303 | 0.8365 | |
BT-474 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12056.145 | 0.8812 | 0.7193 | 0.8365 |