Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 10998.144 | 0.4166 | -0.3167 | 0.8153 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 10998.144 | 1.0896 | 1.2219 | 0.8153 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 10998.144 | 0.8358 | 0.6051 | 0.8153 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 12206.144 | 0.9782 | 0.9556 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 12206.144 | 0.8988 | 0.7939 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 12206.144 | 1.0261 | 1.0533 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 12206.144 | 0.9765 | 0.9520 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 12206.144 | 0.9392 | 0.8761 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 12206.144 | 0.9926 | 0.9849 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 12206.144 | 0.5456 | 0.0785 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 12206.144 | 0.9031 | 0.8026 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 12206.144 | 0.5491 | 0.0857 | 0.9811 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12594.168 | 0.9931 | 0.9891 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12594.168 | 1.0345 | 1.0540 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12594.168 | 0.9912 | 0.9861 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12594.168 | 1.0292 | 1.0458 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12594.168 | 0.9803 | 0.9689 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12594.168 | 0.9982 | 0.9972 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 8 | uM | 12594.168 | 1.0250 | 1.0392 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 40 | uM | 12594.168 | 1.0135 | 1.0213 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | JNK-IN-5A | JNK | JNK | 200 | uM | 12594.168 | 0.2635 | -0.3001 | 1.2703 | |
| MDA-MB-175-VII | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 10642.144 | 1.0212 | 1.0654 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 10642.144 | 0.8970 | 0.6924 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 10642.144 | 0.9617 | 0.8834 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 10642.144 | 0.9461 | 0.8368 | 0.6510 |