Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11938.144 | 0.9755 | 0.9246 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11938.144 | 0.9232 | 0.7666 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11938.144 | 0.9771 | 0.9293 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11938.144 | 0.9598 | 0.8768 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11938.144 | 0.3336 | -0.6359 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11938.144 | 0.4433 | -0.4340 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 11938.144 | 0.4474 | -0.4259 | 0.6445 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000341 | uM | 11660.144 | 1.0356 | 1.0692 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00171 | uM | 11660.144 | 0.9267 | 0.8573 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00853 | uM | 11660.144 | 0.9615 | 0.9251 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0427 | uM | 11660.144 | 1.0253 | 1.0492 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.213 | uM | 11660.144 | 1.0121 | 1.0236 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.07 | uM | 11660.144 | 0.6119 | 0.2403 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 5.33 | uM | 11660.144 | 0.7200 | 0.4529 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 26.7 | uM | 11660.144 | 0.7077 | 0.4286 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 133 | uM | 11660.144 | 0.6072 | 0.2310 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.000512 | uM | 12003.168 | 0.9953 | 0.9918 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.00256 | uM | 12003.168 | 0.9844 | 0.9726 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.0128 | uM | 12003.168 | 0.9868 | 0.9768 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.064 | uM | 12003.168 | 0.9442 | 0.9016 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 0.32 | uM | 12003.168 | 0.8878 | 0.8013 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 1.6 | uM | 12003.168 | 0.9744 | 0.9549 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 8 | uM | 12003.168 | 0.6647 | 0.3964 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 40 | uM | 12003.168 | 0.7104 | 0.4806 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | JNK-IN-5A | JNK | JNK | 200 | uM | 12003.168 | 0.7821 | 0.6113 | 1.1370 |