Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 12608.171 | 0.9837 | 0.9693 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 12608.171 | 0.9545 | 0.9144 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 12608.171 | 0.9727 | 0.9487 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 0.267 | uM | 12608.171 | 0.9880 | 0.9774 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 1.33 | uM | 12608.171 | 0.9427 | 0.8921 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 6.67 | uM | 12608.171 | 0.8815 | 0.7764 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | ICRF-193 | TOP2 | TOP | 33.3 | uM | 12608.171 | 0.7755 | 0.5749 | 1.0643 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.0000853 | uM | 10580.139 | 0.9182 | 0.8274 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 10580.139 | 0.8983 | 0.7855 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 10580.139 | 0.9382 | 0.8697 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 10580.139 | 1.0051 | 1.0108 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 10580.139 | 1.0277 | 1.0586 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10580.139 | 0.9434 | 0.8804 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10580.139 | 0.9277 | 0.8475 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10580.139 | 0.8753 | 0.7373 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10580.139 | 0.9570 | 0.9092 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.0000853 | uM | 10754.151 | 0.9352 | 0.8648 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.000427 | uM | 10754.151 | 0.9983 | 0.9965 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.00213 | uM | 10754.151 | 0.9994 | 0.9988 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.0107 | uM | 10754.151 | 1.0173 | 1.0362 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.0533 | uM | 10754.151 | 1.0263 | 1.0549 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 0.267 | uM | 10754.151 | 0.8563 | 0.7011 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 1.33 | uM | 10754.151 | 0.9296 | 0.8532 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 6.67 | uM | 10754.151 | 0.8100 | 0.6050 | 0.9579 | |
| UACC-812 | HER2amp | Luminal | ICRF-193 | TOP2 | TOP | 33.3 | uM | 10754.151 | 0.7686 | 0.5195 | 0.9579 |