Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 7918.001 | 0.1090 | -0.0732 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 7918.001 | 0.0417 | -0.3358 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 7918.001 | 0.0736 | -0.1913 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 7918.001 | 0.0063 | -0.6546 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7920.001 | 1.0657 | 1.0291 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7920.001 | 1.0518 | 1.0230 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7920.001 | 0.9771 | 0.9895 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7920.001 | 0.5667 | 0.7582 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7920.001 | 0.1999 | 0.3881 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 7920.001 | 0.0864 | 0.1476 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 7920.001 | 0.0527 | 0.0258 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 7920.001 | 0.0740 | 0.1080 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 7920.001 | 0.0667 | 0.0820 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9844.001 | 1.0113 | 1.0096 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9844.001 | 1.0713 | 1.0593 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9844.001 | 1.0944 | 1.0780 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9844.001 | 1.0204 | 1.0172 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9844.001 | 0.1310 | -0.1552 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 0.267 | uM | 9844.001 | 0.0956 | -0.2608 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 1.33 | uM | 9844.001 | 0.0642 | -0.3755 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 6.67 | uM | 9844.001 | 0.0876 | -0.2875 | 2.3587 | |
| SUM159PT | TNBC | Basal B | GSK461364 | PLK1 | PLK | 33.3 | uM | 9844.001 | 0.0119 | -0.6948 | 2.3587 | |
| SUM185PE | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10146.001 | 1.0646 | 1.1777 | 0.7356 | |
| SUM185PE | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10146.001 | 1.1430 | 1.3986 | 0.7356 | |
| SUM185PE | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10146.001 | 1.0972 | 1.2689 | 0.7356 |