Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7477.091 | 1.0195 | 1.0338 | 1.1485 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7477.091 | 0.8205 | 0.6835 | 1.1485 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7477.091 | 1.0494 | 1.0857 | 1.1485 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7477.091 | 0.5433 | 0.1758 | 1.1485 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7477.091 | 0.1947 | -0.5189 | 1.1485 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7477.091 | 0.0011 | -0.9946 | 1.1485 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7477.091 | 0.0021 | -0.9908 | 1.1485 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7477.098 | 0.9209 | 0.8876 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7477.098 | 0.7257 | 0.5970 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7477.098 | 0.8113 | 0.7269 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7477.098 | 0.9182 | 0.8836 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7477.098 | 0.9191 | 0.8850 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7477.098 | 1.4374 | 1.5801 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7477.098 | 0.4273 | 0.1012 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7477.098 | 0.0570 | -0.7323 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7477.098 | 0.2849 | -0.1715 | 1.4247 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 10380.092 | 1.0346 | 1.0462 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 10380.092 | 1.1272 | 1.1675 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 10380.092 | 0.9831 | 0.9773 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 10380.092 | 1.1479 | 1.1941 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 10380.092 | 1.0307 | 1.0410 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 10380.092 | 0.5756 | 0.3801 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 10380.092 | 0.4544 | 0.1774 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 10380.092 | 0.4732 | 0.2099 | 1.4888 | |
| LY2 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 10380.092 | 0.4528 | 0.1747 | 1.4888 |