Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7816.001 | 1.0543 | 1.1061 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7816.001 | 0.9774 | 0.9559 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7816.001 | 1.0606 | 1.1182 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7816.001 | 1.0332 | 1.0649 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7816.001 | 0.5437 | 0.1032 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7816.001 | 0.3322 | -0.3180 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7816.001 | 0.3472 | -0.2880 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7816.001 | 0.2990 | -0.3847 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7816.001 | 0.0610 | -0.8697 | 1.0243 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9254.001 | 1.0763 | 1.4051 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9254.001 | 1.1821 | 2.0429 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9254.001 | 0.9799 | 0.9009 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9254.001 | 1.2002 | 2.1617 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9254.001 | 0.5325 | -0.5885 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9254.001 | 0.5184 | -0.6153 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9254.001 | 0.5570 | -0.5393 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9254.001 | 0.4322 | -0.7563 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9254.001 | 0.1219 | -0.9898 | 0.3986 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9258.001 | 0.8815 | 0.6761 | 0.7137 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9258.001 | 0.9973 | 0.9925 | 0.7137 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9258.001 | 0.9833 | 0.9533 | 0.7137 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9258.001 | 0.9868 | 0.9630 | 0.7137 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9258.001 | 0.5771 | -0.0742 | 0.7137 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9258.001 | 0.3724 | -0.4990 | 0.7137 | |
| HCC1395 | TNBC | Basal B | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9258.001 | 0.3111 | -0.6104 | 0.7137 |